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Article

Higher RET Gene Expression Levels Do Not Represent anAlternative RET Activation Mechanism in Medullary Thyroid Carcinoma.

Biomolecules - 19 Oct 2021

Mulè Chiara, Ciampi Raffaele, Ramone Teresa, Prete Alessandro, Matrone Antonio, Cappagli Virginia, Torregrossa Liborio, Basolo Fulvio, Elisei Rossella, Romei Cristina

Abstract excerpt

This study was designed to investigate whether RET (rearranged during transfection) mRNA over-expression could be considered an alternative driver event for the development of medullary thyroid carcinoma (MTC), and if different RET isoforms could play a role in MTC tumorigenesis. Eighty-three MTC patients, whose mutational profile was previously identified by next-generation sequencing (NGS) IONS5, were included...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34680178
DOI: 10.3390/biom11101542
PMCID: PMC8533768

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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