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Article

Alzheimer disease-like clinical phenotype in a family with FTDP-17 caused by a MAPT R406W mutation.

European journal of neurology - 1 Apr 2008

Lindquist S G, Holm I E, Schwartz M, Law I, Stokholm J, Batbayli M, Waldemar G, Nielsen J E

Abstract excerpt

We report clinical, molecular, neuroimaging and neuropathological features of a Danish family with autosomal dominant inherited dementia, a clinical phenotype resembling Alzheimer's disease and a pathogenic mutation (R406W) in the microtubule associated protein tau (MAPT) gene. Pre-symptomatic an...

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Source

Identifiers

PMID: 18284428
DOI: 10.1111/j.1468-1331.2008.02069.x

Genes

MAPT

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18284428-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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