Article
Cognitive Frailty: A Systematic Review of Epidemiological and Neurobiological Evidence of an Age-Related Clinical Condition.
Rejuvenation research - 1 Oct 2015
Panza Francesco, Solfrizzi Vincenzo, Barulli Maria Rosaria, Santamato Andrea, Seripa Davide, Pilotto Alberto, Logroscino Giancarlo
Abstract excerpt
Advancing age is the focus of recent studies on familial and sporadic Alzheimer's disease (AD), suggesting a prolonged pre-clinical phase several decades before the onset of dementia symptoms. Influencing some age-related conditions, such as frailty, may have an impact on the prevention of late-life cognitive disorders. Frailty reflects a nonspecific state of vulnerability and a multi-system physiological change...
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