Article
Association of HLA-DRB1, DQA1 and DQB1 alleles and haplotype in Parkinson's disease from South India.
Neuroscience letters - 20 Nov 2021
Pandi Sasiharan, Chinniah Rathika, Sevak Vandit, Ravi Padma Malini, Raju Muthuppandi, Vellaiappan Neethi Arasu, Karuppiah Balakrishnan
Abstract excerpt
Parkinson's disease (PD) is a chronic, neurodegenerative motor disease exhibiting familial and sporadic forms. The present study was aimed to elucidate the association of HLA-DRB1*, DQA1* and DQB1* alleles with PD. A total of 105 PD patients and 100 healthy controls were typed by PCR-SSP method. We further carried out high-resolution genotyping for DQB1 and DQA1. Results revealed the increased frequencies of...
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