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Article

Association of HLA-A, B, DRB1* and DQB1* alleles and haplotypes in south Indian T2DM patients.

Gene - 30 Oct 2016

Chinniah Rathika, Vijayan Murali, Sivanadham Ramgopal, Ravi Padma Malini, Panneerselvam Dharmarajan, Karuppiah Balakrishnan

Abstract excerpt

The genes of Human Leukocyte Antigen (HLA) system are implicated in the susceptibility of several diseases including Type 2 diabetes (T2DM). Therefore, we aimed to investigate the association of HLA alleles with T2DM in south India. A total of 344 patients (195 males; 149 females) and 309 controls (186 males; 123 females) were genotyped for HLA-DR/-DQ alleles. Based on predominant DR/DQ haplotypes, 222 patients...

Topics

Adult
Aged
Alleles
Case-Control Studies
Diabetes Mellitus, Type 2
Female
HLA-A Antigens
HLA-B Antigens
HLA-DQ beta-Chains
HLA-DRB1 Chains
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

India

Male

Middle Aged

Source

Identifiers

PMID: 27496342
DOI: 10.1016/j.gene.2016.08.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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