Article
Genetic analysis of HLA-DRA region variation in Taiwanese Parkinson's disease.
Parkinsonism & related disorders - 1 May 2012
Chiang Han-Lin, Lee-Chen Guey-Jen, Chen Chiung Mei, Chen Yi-Chun, Lee Chei-Mei, Liao Ming-Hui, Wu Yih-Ru
Abstract excerpt
Parkinson's disease (PD) is a neurodegenerative disorder comprising both motor and cognitive disability. The pathogenesis of the disease is still unclear; however, neuroinflammation seemed to play a role. A recent genome-wide association study (GWAS) reported an association between HLA-DRA rs3129882 and the development of PD in Caucasian populations. In this study, we observe no association between this single...
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