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Article

Dengue virus is sensitive to inhibition prior to productive replication.

Cell reports - 12 Oct 2021

Talemi Soheil Rastgou, Bartenschlager Marie, Schmid Bianca, Ruggieri Alessia, Bartenschlager Ralf, Höfer Thomas

Abstract excerpt

Uncovering vulnerable steps in the life cycle of viruses supports the rational design of antiviral treatments. However, information on viral replication dynamics obtained from traditional bulk assays with host cell populations is inherently limited as the data represent averages over a multitude of unsynchronized replication cycles. Here, we use time-lapse imaging of virus replication in thousands of single...

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PMID: 34644578
DOI: 10.1016/j.celrep.2021.109801

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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