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Inhibition of infection spread by co-transmitted defective interfering particles

15 Sept 2017

Abstract excerpt

Although virus release from host cells and tissues propels the spread of many infectious diseases, most virus particles are not infectious; many are defective, lacking essential genetic information needed for replication. When defective and viable particles enter the same cell, the defective particles can multiply while interfering with viable particle production. Defective interfering particles (DIPs) occur in...

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PMID: 28915264
DOI: 10.1371/journal.pone.0184029

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