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Article

Chloride transport modulators as drug candidates.

American journal of physiology. Cell physiology - 1 Dec 2021

Verkman Alan S, Galietta Luis J V

Abstract excerpt

Chloride transport across cell membranes is broadly involved in epithelial fluid transport, cell volume and pH regulation, muscle contraction, membrane excitability, and organellar acidification. The human genome encodes at least 53 chloride-transporting proteins with expression in cell plasma or intracellular membranes, which include chloride channels, exchangers, and cotransporters, some having broad anion...

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Identifiers

PMID: 34644122
DOI: 10.1152/ajpcell.00334.2021
PMCID: PMC8714991

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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