Article
On the discovery and development of CFTR chloride channel activators.
Current pharmaceutical design - 1 Jan 2006
Becq Frédéric
Abstract excerpt
Chloride channels play important roles in vital cellular signalling processes contributing to homeostasis in both excitable and non-excitable cells. Since 1987, more than ten ion channel genes have been identified as causing human hereditary diseases among them the genes for the voltage-dependent...
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