Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ion Channel Modulators in Cystic Fibrosis.

Chest - 1 Aug 2018

Gentzsch Martina, Mall Marcus A

Abstract excerpt

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene and remains one of the most common life-shortening genetic diseases affecting the lung and other organs. CFTR functions as a cyclic adenosine monophosphate-dependent anion channel that transports chloride and bicarbonate across epithelial surfaces, and disruption of these ion transport processes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chloride Channel Agonists
Share to Drug Combinations
Share to Indoles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ion Channels

Share to Quinolones

Share to Aminophenols

Share to Aminopyridines

Share to Benzodioxoles

Source

Open in PubMed Open full text

Identifiers

PMID: 29750923
DOI: 10.1016/j.chest.2018.04.036
PMCID: PMC6113631

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ion Channel Modulators in Cystic Fibrosis.PMID 29750923Read ↗

Targeting ion channels in cystic fibrosis.Semantic proximity Read ↗

Discovery of CFTR modulators for the treatment of cystic fibrosis.Semantic proximity Read ↗

Cystic fibrosis transmembrane conductance regulator modulators: precision medicine in cystic fibrosisSemantic proximity Read ↗

Targeting a genetic defect: cystic fibrosis transmembrane conductance regulator modulators in cystic fibrosis.Semantic proximity Read ↗

Lumacaftor and ivacaftor in the management of patients with cystic fibrosis: current evidence and future prospects.Semantic proximity Read ↗

CFTR Modulators: Current Status and Evolving Knowledge.Semantic proximity Read ↗

Small-molecule drugs for cystic fibrosis: Where are we now?Semantic proximity Read ↗

CFTR Modulators: Shedding Light on Precision Medicine for Cystic FibrosisSemantic proximity Read ↗

[Treatment of Cystic Fibrosis with CFTR Modulators].Semantic proximity Read ↗

The revolution of personalized pharmacotherapies for cystic fibrosis: what does the future hold?Semantic proximity Read ↗

Cystic fibrosis: a model system for precision medicine.Semantic proximity Read ↗

Personalized medicine in CF: from modulator development to therapy for cystic fibrosis patients with rare CFTR mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.