Article
Effects of HIV infection and ART on phenotype and function of circulating monocytes, natural killer, and innate lymphoid cells.
AIDS research and therapy - 15 Mar 2018
Nabatanzi Rose, Cose Stephen, Joloba Moses, Jones Sarah Rowland, Nakanjako Damalie
Abstract excerpt
HIV infection causes upregulation of markers of inflammation, immune activation and apoptosis of host adaptive, and innate immune cells particularly monocytes, natural killer (NK) and innate lymphoid cells (ILCs). Although antiretroviral therapy (ART) restores CD4 T-cell counts, the persistent aberrant activation of monocytes, NK and ILCs observed likely contributes to the incomplete recovery of T-cell effector...
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