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Article

Brain Versus Blood: A Systematic Review on the Concordance Between Peripheral and Central Kynurenine Pathway Measures in Psychiatric Disorders.

Frontiers in immunology - 1 Jan 2021

Skorobogatov Katrien, De Picker Livia, Verkerk Robert, Coppens Violette, Leboyer Marion, Müller Norbert, Morrens Manuel

Abstract excerpt

Objective: Disturbances in the kynurenine pathway have been implicated in the pathophysiology of psychotic and mood disorders, as well as several other psychiatric illnesses. It remains uncertain however to what extent metabolite levels detectable in plasma or serum reflect brain kynurenine metabolism and other disease-specific pathophysiological changes. The primary objective of this systematic review was to...

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Identifiers

PMID: 34630391
DOI: 10.3389/fimmu.2021.716980
PMCID: PMC8495160

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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