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Kynurenine pathway in post-mortem prefrontal cortex and cerebellum in schizophrenia: relationship with monoamines and symptomatology

2021-02-22

Abstract excerpt

<h4>Background</h4> the cortico-cerebellar-thalamic-cortical circuit has been implicated in the emergence of psychotic symptoms in schizophrenia (SZ). The kynurenine pathway (KP) has been linked to alterations in glutamatergic and monoaminergic neurotransmission and to SZ symptomatology through the production of the metabolites quinolinic acid (QA) and kynurenic acid (KYNA). <h4>Methods</h4> this work describes...

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Literature Corpus work
06b3fdc4-580c-5458-9dd9-1f0e46548341
DOI
10.1101/2021.02.22.432214
Open publication

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Kynurenine pathway in post-mortem prefrontal cortex and cerebellum in schizophrenia: relationship with monoamines and symptomatologyDOI 10.1101/2021.02.22.432214
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