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Article

Intraocular iron injection induces oxidative stress followed by elements of geographic atrophy and sympathetic ophthalmia

9 Oct 2021

Abstract excerpt

Iron has been implicated in the pathogenesis of age-related retinal diseases, including age-related macular degeneration (AMD). Previous work showed that intravitreal (IVT) injection of iron induces acute photoreceptor death, lipid peroxidation, and autofluorescence (AF). Herein, we extend this work, finding surprising chronic features of the model: geographic atrophy and sympathetic ophthalmia. We provide new...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34626070
DOI: 10.1111/acel.13490

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