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The intersection of mitochondria, lipids, and ferroptosis: a new avenue for dry age-related macular degeneration

21 Aug 2025

Abstract excerpt

Age-related macular degeneration (AMD) is currently the leading cause of vision loss in developed countries. Despite decades of research and development, there are currently no treatments for the dry version of the illness. Dry AMD (DAMD) is a multifactorial disease stemming from dysfunction in the complement system, mitochondrial function, and lipid metabolism. While the complement system has been studied...

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PMID: 40839325
DOI: 10.1007/s10495-025-02165-2

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