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Function of Oncogene Mycn in Adult Neurogenesis and Oligodendrogenesis

8 Oct 2021

Abstract excerpt

Human MYCN is an oncogene amplified in neuroblastoma and many other tumors. Both human MYCN and mouse Mycn genes are important in embryonic brain development, but their functions in adult healthy nerve system are completely unknown. Here, with Mycn-eGFP mice and quantitative RT-PCR, we found that Mycn was expressed in specific brain regions of young adult mice, including subventricular zone (SVZ), subgranular...

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Glioma Diagnosis and Treatment
Microtubule and mitosis dynamics
Neuroblastoma Research and Treatments

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34625907
DOI: 10.1007/s12035-021-02584-7

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