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Article

Phox2B correlates with MYCN and is a prognostic marker for neuroblastoma development

31 Mar 2015

Abstract excerpt

Neuroblastoma is the one of the most common extracranial childhood malignancies, accounting for ~15% of tumor‑associated deaths in children. It is generally considered that neuroblastoma originates from neural crest cells in the paravertebral sympathetic ganglia and the adrenal medulla. However, the mechanism by which neuroblastoma arises during sympathetic neurogenesis and the cellular mechanism that drives...

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PMID: 26137098
DOI: 10.3892/ol.2015.3088

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