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Article

Myc proteins in brain tumor development and maintenance.

Upsala journal of medical sciences - 1 May 2012

Swartling Fredrik J

Abstract excerpt

Myc proteins are often deregulated in human brain tumors, especially in embryonal tumors that affect children. Many observations have shown how alterations of these pleiotropic Myc transcription factors provide initiation, maintenance, or progression of tumors. This review will focus on the role of Myc family members (particularly c-myc and Mycn) in tumors like medulloblastoma and glioma and will further discuss...

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Identifiers

PMID: 22348395
DOI: 10.3109/03009734.2012.658975
PMCID: PMC3339544

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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