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Article

c-myc and N-myc promote active stem cell metabolism and cycling as architects of the developing brain.

Oncotarget - 1 Jun 2010

Wey Alice, Knoepfler Paul S

Abstract excerpt

myc genes are associated with a wide variety of human cancers including most types of nervous system tumors. While the mechanisms by which myc overexpression causes tumorigenesis are multifaceted and have yet to be clearly elucidated, they are at least in part related to endogenous myc function in normal cells. Knockout (KO) of either c-myc or N-myc genes in neural stem and precursor cells (NSC) driven by...

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Identifiers

PMID: 20651942
DOI: 10.18632/oncotarget.116
PMCID: PMC2907900

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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