Sonic Hedgehog signalling in the regulation of barrier tissue homeostasis and inflammation

Abstract excerpt

Epithelial barrier tissues such as the skin and airway form an essential interface between the mammalian host and its external environment. These physical barriers are crucial to prevent damage and disease from environmental insults and allergens. Failure to maintain barrier function against such risks can lead to severe inflammatory disorders, including atopic dermatitis and asthma. Here, we discuss the role of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Congenital gastrointestinal and neural anomalies
• Share to Hedgehog Signaling Pathway Studies