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Article

The emerging role of the hedgehog signaling pathway in immunity response and autoimmune diseases

23 Sept 2023

Abstract excerpt

The Hedgehog (Hh) family is a prototypical morphogen involved in embryonic patterning, multi-lineage differentiation, self-renewal, morphogenesis, and regeneration. There are studies that have demonstrated that the Hh signaling pathway differentiates developing T cells into MHC-restricted self-antigen tolerant T cells in a concentration-dependent manner in the thymus. Whereas Hh signaling pathway is not required...

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PMID: 37740690
DOI: 10.1080/08916934.2023.2259127

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