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Article

Tissue-Derived Hedgehog Proteins Modulate Th Differentiation and Disease

13 Feb 2013

Abstract excerpt

Genome-wide association studies of complex immune-mediated diseases have indicated that many genetic factors, each with individual low risk, contribute to overall disease. It is therefore timely and important to characterize how immune responses may be subtly modified by tissue context. In this article, we explore the role of tissue-derived molecules in influencing the function of T cells, which, owing to their...

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PMID: 23408837
DOI: 10.4049/jimmunol.1202541

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