Article

An essential function for autocrine Hedgehog signaling in epithelial proliferation and differentiation in the trachea

2022-01-14

Abstract excerpt

The tracheal epithelium is a primary target for pulmonary diseases as it provides a conduit for air flow between the environment and the lung lobes. The cellular and molecular mechanisms underlying airway epithelial cell proliferation and differentiation remain poorly understood. Hedgehog (Hh) signaling orchestrates communication between epithelial and mesenchymal cells in the lung, where it modulates stromal cell...

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Literature Corpus work: a8ab2c09-a158-5710-870b-c643c39009e1
DOI: 10.1101/2022.01.13.476169

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