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Article

Multilayer spectrum of intratumoral heterogeneity in basal bladder cancer.

The Journal of pathology - 1 Jan 2022

Sirab Nanor, Drubay Damien, Maillé Pascale, Popova Tatiana, Ngo Carine, Gentien David, Moktefi Anissa, Soyeux-Porte Pascale, Pelletier Romain, Reyes Cécile, Henry Emilie, Pouessel Damien, Vordos Dimitri, Lebret Thierry, de Reyniès Aurélien, Paoletti Xavier, Radvanyi François, Allory Yves

Abstract excerpt

Basal/squamous (Ba/Sq) subtype represents an intrinsic and robust group in the consensus molecular classification of muscle-invasive bladder cancer (MIBC), with poor outcome and controversial chemosensitivity. We aimed to investigate the spectrum of intratumor heterogeneity (ITH) in the Ba/Sq subtype. First, we validated a 29-gene NanoString CodeSet to predict the Ba/Sq subtype for FFPE samples. We identified...

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Identifiers

PMID: 34611919
DOI: 10.1002/path.5813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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