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Development and validation of an intra-tumor heterogeneity-related signature to predict prognosis of bladder cancer: a study based on single-cell RNA-seq

2 Aug 2021

Abstract excerpt

Intra-tumor heterogeneity (ITH) was a potential mechanism of progression and drug resistance in bladder cancer (BCa). However, the understanding of ITH in BCa remains insufficient. Single-cell RNA sequencing (scRNA-seq) profiles of 2075 cells were analyzed, and 2940 cell markers were screened. The ITH of 396 cases was evaluated, and 96 ITH-related genes were identified. Based on the gene-pair strategy, 96 genes...

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Share to Bladder and Urothelial Cancer Treatments
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34339395
DOI: 10.18632/aging.203353

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