Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Consensus subtypes of hepatocellular carcinoma associated with clinical outcomes and genomic phenotypes.

Hepatology (Baltimore, Md.) - 1 Dec 2022

Lee Sung Hwan, Yim Sun Young, Jeong Yun Seong, Li Qi-Xiang, Kang Sang-Hee, Sohn Bo Hwa, Kumar Shwetha V, Shin Ji-Hyun, Choi You Rhee, Shim Jae-Jun, Kim Hayeon, Kim Ji Hoon, Kim Shin, Guo Sheng, Johnson Randy L, Kaseb Ahmed, Kang Koo Jeong, Chun Yun Shin, Jang Hee Jin, Lee Byoung Gill, Woo Hyun Goo, Ha Min Jin, Akbani Rehan, Roberts Lewis R, Wheeler David A, Lee Ju-Seog

Abstract excerpt

BACKGROUND AND AIMS: Although many studies revealed transcriptomic subtypes of HCC, concordance of the subtypes are not fully examined. We aim to examine a consensus of transcriptomic subtypes and correlate them with clinical outcomes. APPROACH AND RESULTS: By integrating 16 previously established genomic signatures for HCC subtypes, we identified five clinically and molecularly distinct consensus subtypes. STM...

Topics

Join the communities discussing this publication.

beta Catenin
Carcinoma, Hepatocellular
Consensus
Genomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hepatocellular Carcinoma Treatment and Prognosis

Liver Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 35349735
DOI: 10.1002/hep.32490
PMCID: PMC9519807

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Consensus subtypes of hepatocellular carcinoma associated with clinical outcomes and genomic phenotypes.PMID 35349735Read ↗

Molecular classification of hepatocellular carcinoma: potential therapeutic implicationsSemantic proximity Read ↗

Novel hepatocellular carcinomas (HCC) Subtype-Specific BiomarkersSemantic proximity Read ↗

Genomic characterization of rare molecular subclasses of hepatocellular carcinoma.Semantic proximity Read ↗

Decoding Liver Cancer Prognosis: From Multi-omics Subtypes, Prognostic Models to Single Cell ValidationSemantic proximity Read ↗

Understanding the heterogeneity in liver hepatocellular carcinoma with a special focus on malignant cell through single-cell analysisSemantic proximity Read ↗

Molecular subtyping of hepatocellular carcinoma: A step toward precision medicineSemantic proximity Read ↗

Histological subtypes of hepatocellular carcinoma are related to gene mutations and molecular tumour classification.Semantic proximity Read ↗

Integrative Transcriptome Analysis Reveals Common Molecular Subclasses of Human Hepatocellular CarcinomaSemantic proximity Read ↗

Comprehensive molecular and immunological characterization of hepatocellular carcinomaSemantic proximity Read ↗

Genetic diversity of hepatocellular carcinomas and its potential impact on targeted therapies.Semantic proximity Read ↗

Single-Cell Transcriptome Analysis Identifies Novel Biomarkers Involved in Major Liver Cancer SubtypesSemantic proximity Read ↗

Hallmark-guided subtypes of hepatocellular carcinoma for the identification of immune-related gene classifiers in the prediction of prognosis, treatment efficacy, and drug candidatesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.