Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma.

Cell - 15 Jun 2017

Abstract excerpt

Liver cancer has the second highest worldwide cancer mortality rate and has limited therapeutic options. We analyzed 363 hepatocellular carcinoma (HCC) cases by whole-exome sequencing and DNA copy number analyses, and we analyzed 196 HCC cases by DNA methylation, RNA, miRNA, and proteomic expression also. DNA sequencing and mutation analysis identified significantly mutated genes, including LZTR1, EEF1A1, SF3B1,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to DNA Methylation
Share to ALB gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomics

Share to Isocitrate Dehydrogenase

Share to Liver Neoplasms

Share to MicroRNAs

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 28622513
DOI: 10.1016/j.cell.2017.05.046
PMCID: PMC5680778

Genes

ALB
APOB
CPS1
EEF1A1
IDH1
LZTR1
MCL1
MDM4
MET
SF3B1
SMARCA4
TERT
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma.PMID 28622513Read ↗

Advances in genomic hepatocellular carcinoma researchSemantic proximity Read ↗

Novel insights into the molecular heterogeneity of hepatocellular carcinomaSemantic proximity Read ↗

Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma.Semantic proximity Read ↗

Comprehensive molecular and immunological characterization of hepatocellular carcinomaSemantic proximity Read ↗

Integrated genomic analyses of hepatocellular carcinoma.Semantic proximity Read ↗

Integrative Genomic Analysis Identifies the Core Transcriptional Hallmarks of Human Hepatocellular CarcinomaSemantic proximity Read ↗

Functional genomic studies: insights into the pathogenesis of liver cancer.Semantic proximity Read ↗

Molecular subtyping of hepatocellular carcinoma: A step toward precision medicineSemantic proximity Read ↗

The changing landscape of hepatocellular carcinoma: etiology, genetics, and therapy.Semantic proximity Read ↗

Identification of drivers from cancer genome diversity in hepatocellular carcinoma.Semantic proximity Read ↗

Diverse modes of genomic alteration in hepatocellular carcinoma.Semantic proximity Read ↗

Whole genome and RNA sequencing analyses for 254 Taiwanese hepatocellular carcinomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.