Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Efficient generation of functional haploid spermatids from human germline stem cells by three-dimensional-induced system

5 Jan 2018

Abstract excerpt

Generation of functional spermatids from human spermatogonial stem cells (SSCs) in vitro is of utmost importance for uncovering mechanisms underlying human germ cell development and treating infertility. Here we report a three-dimensional-induced (3D-I) system by which human SSCs were efficiently differentiated into functional haploid spermatids. Human SSCs were isolated and identified phenotypically. Meiotic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Pluripotent Stem Cells Research
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29305586
DOI: 10.1038/s41418-017-0015-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Efficient generation of functional haploid spermatids from human germline stem cells by three-dimensional-induced systemPMID 29305586Read ↗

Generation of Haploid Spermatids with Fertilization and Development Capacity from Human Spermatogonial Stem Cells of Cryptorchid PatientsSemantic proximity Read ↗

Derivation and propagation of spermatogonial stem cells from human pluripotent cellsSemantic proximity Read ↗

Spermatogonial Stem Cells for In Vitro Spermatogenesis and In Vivo Restoration of FertilitySemantic proximity Read ↗

Transcriptomic and epigenomic profiling of young and aged spermatogonial stem cells reveals molecular targets regulating differentiationSemantic proximity Read ↗

Generation of male differentiated germ cells from various types of stem cells.Semantic proximity Read ↗

Transcriptomic and epigenomic profiling of young and aged spermatogonial stem cells reveals molecular targets regulating differentiationSemantic proximity Read ↗

Spermatogonial stem cells of the testis.Semantic proximity Read ↗

Genome-wide DNA methylation changes in human spermatogenesisSemantic proximity Read ↗

Applications of single-cell RNA sequencing in spermatogenesis and molecular evolutionSemantic proximity Read ↗

Offspring production of ovarian organoids derived from spermatogonial stem cells by defined factors with chromatin reorganizationSemantic proximity Read ↗

Offspring production of ovarian organoids derived from spermatogonial stem cells by chromatin reorganizationSemantic proximity Read ↗

Roles of Spermatogonial Stem Cells in Spermatogenesis and Fertility RestorationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.