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Article

Docosahexaenoic acid normalizes QT interval in long QT type 2 transgenic rabbit models in a genotype-specific fashion.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology - 2 Mar 2022

Castiglione Alessandro, Hornyik Tibor, Wülfers Eike M, Giammarino Lucilla, Edler Iask, Jowais Jessica J, Rieder Marina, Perez-Feliz Stefanie, Koren Gideon, Bősze Zsuzsanna, Varró András, Zehender Manfred, Brunner Michael, Bode Christoph, Liin Sara I, Larsson Hans Peter, Baczkó István, Odening Katja E

Abstract excerpt

AIM: Long QT syndrome (LQTS) is a cardiac channelopathy predisposing to ventricular arrhythmias and sudden cardiac death. Since current therapies often fail to prevent arrhythmic events in certain LQTS subtypes, new therapeutic strategies are needed. Docosahexaenoic acid (DHA) is a polyunsaturated fatty acid, which enhances the repolarizing IKs current. METHODS AND RESULTS: We investigated the effects of DHA in...

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Identifiers

PMID: 34601592
DOI: 10.1093/europace/euab228
PMCID: PMC9125797

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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