Regional TMPRSS2 V197M Allele Frequencies Are Correlated with COVID-19 Case Fatality Rates.

doi:10.14348/molcells.2021.2249

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Regional TMPRSS2 V197M Allele Frequencies Are Correlated with COVID-19 Case Fatality Rates.

Molecules and cells - 30 Sept 2021

Jeon Sungwon, Blazyte Asta, Yoon Changhan, Ryu Hyojung, Jeon Yeonsu, Bhak Youngjune, Bolser Dan, Manica Andrea, Shin Eun-Seok, Cho Yun Sung, Kim Byung Chul, Ryoo Namhee, Choi Hansol, Bhak Jong

Abstract excerpt

Coronavirus disease, COVID-19 (coronavirus disease 2019), caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has a higher case fatality rate in European countries than in others, especially East Asian ones. One potential explanation for this regional difference is the diversity of the viral infection efficiency. Here, we analyzed the allele frequencies of a nonsynonymous variant rs12329760...

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PMID: 34588322
DOI: 10.14348/molcells.2021.2249
PMCID: PMC8490206

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