Article

Ethnicity-dependent allele frequencies are correlated with COVID-19 case fatality rate

2020-06-24

Abstract excerpt

<title>Abstract</title> <p>Coronavirus disease (COVID-19), caused by SARS-CoV-2, has a higher case fatality rate (CFR) in European ethnic groups than in others, especially East Asians. One explanation to this phenomenon might be TMPRSS2, a key processing enzyme essential for viral infection. Here, we analyzed the allele frequencies of two nonsynonymous variants rs12329760 (V197M) and rs75603675 (G8V) in the <ital...

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Literature Corpus work: 2fe51359-01d9-5ea5-b703-e6e965eb8f78
DOI: 10.21203/rs.3.rs-37798/v1

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