Article

Ethnicity-dependent allele frequencies are correlated with COVID-19 case fatality rate

2020-10-16

Abstract excerpt

Coronavirus disease (COVID-19), caused by SARS-CoV-2, has a higher case fatality rate (CFR) in European ethnic groups than in others, especially East Asians. One explanation to this phenomenon might be TMPRSS2, a key processing enzyme essential for viral infection. Here, we analyzed the allele frequencies of two nonsynonymous variants rs12329760 (V197M) and rs75603675 (G8V) in the TMPRSS2 gene using over 200,000 p...

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Literature Corpus work: 669231cc-591a-53b8-997f-1618b2e074bb
DOI: 10.22541/au.160288495.58916395/v1

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