Article

Genetic association of <i>TMPRSS2</i> rs2070788 polymorphism with COVID-19 Case Fatality Rate among Indian populations

2021-10-05

Abstract excerpt

SARS-CoV2, the causative agent for COVID-19, an ongoing pandemic, engages the ACE2 receptor to enter the host cell through S protein priming by a serine protease, TMPRSS2. Variation in the TMPRSS2 gene may account for the difference in population disease susceptibility. The haplotype-based genetic sharing and structure of TMPRSS2 among global populations have not been studied so far. Therefore, in the present wor...

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Literature Corpus work: 89b540ad-e4c9-5088-a69b-7088c3c65de7
DOI: 10.1101/2021.10.04.463014

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