Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Utility of plasma cell-free DNA for de novo detection and quantification of clonal hematopoiesis.

Haematologica - 1 Aug 2022

Gutierrez-Rodrigues Fernanda, Beerman Isabel, Groarke Emma M, Patel Bhavisha A, Spitofsky Nina, Dillon Laura W, Raffo Diego Quinones, Hourigan Christopher S, Kajigaya Sachiko, Ferrucci Luigi, Young Neal S

Abstract excerpt

Although cell-free DNA (cfDNA) tests have emerged as a potential non-invasive alternative to bone marrow biopsies for monitoring clonal hematopoiesis in hematologic diseases, whether commercial cfDNA assays can be implemented for the detection and quantification of de novo clonal hematopoiesis in place of blood cells is uncertain. In this study, peripheral plasma cfDNA samples available from patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Aplastic
Share to Cell-Free Nucleic Acids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Clonal Hematopoiesis

Share to Hematopoiesis

Share to Mutation

Share to Myelodysplastic Syndromes

Source

Open in PubMed Open full text

Identifiers

PMID: 34587721
DOI: 10.3324/haematol.2021.279230
PMCID: PMC9335099

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Utility of plasma cell-free DNA for de novo detection and quantification of clonal hematopoiesis.PMID 34587721Read ↗

Clonal hematopoiesis detection in cancer patients using cell free DNA sequencingSemantic proximity Read ↗

Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults.Semantic proximity Read ↗

The diagnostic utility of targeted gene panel sequencing in discriminating etiologies of cytopeniaSemantic proximity Read ↗

Clonal cytopenias of undetermined significance: potential predictor of myeloid malignancies?Semantic proximity Read ↗

Molecular and cytogenetic characterization of myelodysplastic syndromes in cell-free DNA.Semantic proximity Read ↗

Myelodysplastic Syndromes Diagnosis: What Is the Role of Molecular Testing?Semantic proximity Read ↗

Genetics and epidemiology of mutational barcode-defined clonal hematopoiesis.Semantic proximity Read ↗

Deep Sequencing of Cell-Free Peripheral Blood DNA as a Reliable Method for Confirming the Diagnosis of Myelodysplastic Syndrome.Semantic proximity Read ↗

High-intensity sequencing reveals the sources of plasma circulating cell-free DNA variants.Semantic proximity Read ↗

Routine clinical mutation profiling using next generation sequencing and a customized gene panel improves diagnostic precision in myeloid neoplasms.Semantic proximity Read ↗

Detection and Characterization of Clonal Hematopoiesis.Semantic proximity Read ↗

Clonal Hematopoiesis of Indeterminate Potential in Patients with Solid Tumor Malignancies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.