Article
Molecular and cytogenetic characterization of myelodysplastic syndromes in cell-free DNA.
Blood advances - 24 May 2022
Garcia-Gisbert Nieves, Garcia-Ávila Sara, Merchán Brayan, Salido Marta, Fernández-Rodríguez Concepción, Gibert Joan, Fernández-Ibarrondo Lierni, Camacho Laura, Lafuente Marta, Longarón Raquel, Espinet Blanca, Vélez Patricia, Pujol Ramon M, Andrade-Campos Marcio, Arenillas Leonor, Salar Antonio, Calvo Xavier, Besses Carles, Bellosillo Beatriz
Abstract excerpt
Molecular and cytogenetic studies are essential for diagnosis and prognosis in patients with myelodysplastic syndromes (MDSs). Cell-free DNA (cfDNA) analysis has been reported to be a reliable noninvasive approach for detecting molecular abnormalities in MDS; however, there is limited information about cytogenetic alterations and monitoring in cfDNA. We assessed the molecular and cytogenetic profile of a cohort...
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