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Article

Analytical protocol to identify local ancestry-associated molecular features in cancer.

STAR protocols - 17 Dec 2021

Carrot-Zhang Jian, Han Seunghun, Zhou Wanding, Damrauer Jeffrey S, Kemal Anab, Cherniack Andrew D, Beroukhim Rameen

Abstract excerpt

People of different ancestries vary in cancer risk and outcome, and their molecular differences may indicate sources of these variations. Determining the "local" ancestry composition at each genetic locus across ancestry-admixed populations can suggest causal associations. We present a protocol to identify local ancestry and detect the associated molecular changes, using data from the Cancer Genome Atlas. This...

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Identifiers

PMID: 34585150
DOI: 10.1016/j.xpro.2021.100766
PMCID: PMC8456058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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