Article
Genetic Ancestry Inference from Cancer-Derived Molecular Data across Genomic and Transcriptomic Platforms.
Cancer research - 4 Jan 2023
Belleau Pascal, Deschênes Astrid, Chambwe Nyasha, Tuveson David A, Krasnitz Alexander
Abstract excerpt
Genetic ancestry-oriented cancer research requires the ability to perform accurate and robust genetic ancestry inference from existing cancer-derived data, including whole-exome sequencing, transcriptome sequencing, and targeted gene panels, very often in the absence of matching cancer-free genomic data. Here we examined the feasibility and accuracy of computational inference of genetic ancestry relying...
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