Article
GSTT1, GSTP1 and XPC genes are associated with longevity in an Italian cohort.
Annals of human biology - 1 Aug 2021
Scarfò Manuel, Sciandra Chiara, Ruberto Stefano, Santovito Alfredo
Abstract excerpt
Longevity is a complex process controlled by environmental and genetic factors. We evaluated the association of seven drug metabolising and DNA-repair gene polymorphisms with longevity in an Italian cohort. A sample of 756 subjects aged 18-98 was genotyped for CYP1A1 (rs1048943, A>G), GSTM1 (rs 1183423000, presence/absence), GSTT1 (rs1601993659, presence/absence), GSTP1 (rs1695, A>G), XRCC1 (rs1799782, C>T),...
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