Article
GSTM1-null polymorphism as possible risk marker for hypertension: results from the aging and longevity study in the Sirente Geographic Area (ilSIRENTE study).
Clinica chimica acta; international journal of clinical chemistry - 1 Jan 2009
Capoluongo Ettore, Onder Graziano, Concolino Paola, Russo Andrea, Santonocito Concetta, Bernabei Roberto, Zuppi Cecilia, Ameglio Franco, Landi Francesco
Abstract excerpt
BACKGROUND: Involvement of various gene mutations in hypertension have been already reported, including GST (detoxification Phase II enzymes), with contrasting results. This study analyzes a possible association between GSTM1-null and GSTT1-null polymorphisms and the hypertension status in a very old population (>80 years). METHODS: 354 old patients were collected (255 were hypertensive and 99 were not). RESULTS:...
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