Article
Analysis of glutathione S-transferase M1 and glutathione S-transferase T1 gene polymorphisms suggests age-related relationships in a northern Italian population.
Archives of toxicology - 1 Dec 2008
Santovito Alfredo, Cervella Piero, Burgarello Claudio, Bigatti Maria Paola, Sella Gabriella, Delpero Massimiliano
Abstract excerpt
The present work attempts to determine the distribution of GSTM1 and GSTT1 genotype and allele frequencies in a sample of northern Italian population, and to examine the age-related association of these polymorphisms. The frequencies of the deleted GSTM1 and GSTT1 genotypes were 0.357 and 0.169, respectively. GSTT1 null-genotype frequency found in this work further confirms data obtained in previous studies of...
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