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APE1/Ref-1 – One Target with Multiple Indications: Emerging Aspects and New Directions

27 Sept 2021

Abstract excerpt

multiple roles of APE1 in cancer and other diseases are summarized. In this Review, we aim to expand on the contributions of APE1 to various diseases and its effect on disease progression. In the scope of cancer, more recent roles for APE1 have been identified in cancer cell metabolism, as well as chemotherapy-induced peripheral neuropathy (CIPN) and inflammation. Outside of cancer, APE1 signaling may be a...

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PMID: 34557865
DOI: 10.33696/signaling.2.047

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