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The role of circadian rhythm regulator PERs in oxidative stress, immunity, and cancer development

16 Jan 2025

Abstract excerpt

The complex interaction between circadian rhythms and physiological functions is essential for maintaining human health. At the heart of this interaction lies the PERIOD proteins (PERs), pivotal to the circadian clock, influencing the timing of physiological and behavioral processes and impacting oxidative stress, immune functionality, and tumorigenesis. PER1 orchestrates the cooperation of the enzyme GPX1,...

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PMID: 39825442
DOI: 10.1186/s12964-025-02040-2

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