Article
Molecular differences in mitochondrial DNA genomes of dogs with malignant mammary tumours.
Veterinary and comparative oncology - 1 Mar 2022
Kowal Krzysztof, Tkaczyk-Wlizło Angelika, Pierzchała Mariusz, Gawor Jan, Ślaska Brygida
Abstract excerpt
The aim of this study was to determine molecular defects in mitochondrial DNA (mtDNA) with the use of large-scale genome analysis in malignant canine mammary gland tumours and indicate whether these changes were linked with the carcinogenesis process. With the use of the NGS technology, we sequenced 27 samples of mtDNA isolated from blood and tumours obtained from 13 dogs with mammary gland tumours. The total...
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