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Genome Aberrations in Canine Mammary Carcinomas and Their Detection in Cell-Free Plasma DNA

30 Sept 2013

Abstract excerpt

Mammary tumors are the most frequent cancers in female dogs exhibiting a variety of histopathological differences. There is lack of knowledge about the genomes of these common dog tumors. Five tumors of three different histological subtypes were evaluated. Massive parallel sequencing (MPS) was performed in comparison to the respective somatic genome of each animal. Copy number and structural aberrations were...

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PMID: 24098698
DOI: 10.1371/journal.pone.0075485

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