Article
Identification of additional mitochondrial DNA mutations in canine mast cell tumours.
Acta veterinaria Scandinavica - 4 May 2016
Śmiech Anna, Ślaska Brygida, Surdyka Magdalena, Grzybowska-Szatkowska Ludmiła, Łopuszyński Wojciech, Różańska Dorota
Abstract excerpt
BACKGROUND: Research has revealed the presence of somatic mutations in mitochondrial DNA (mtDNA) of certain types of tumours. As this has not been studied for canine mast cell tumours, the aim of this study was to identify mutations in the hypervariable region of mtDNA in mast cell tumours in dogs and determine their association with the process of neoplastic transformation. RESULTS: Samples from 17 dogs with...
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