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Article

Low-intensity pulsed ultrasound prevents angiotensin II-induced aortic smooth muscle cell phenotypic switch via hampering miR-17-5p and enhancing PPAR-γ.

European journal of pharmacology - 15 Nov 2021

Zhao Kun, Wu Tingting, Yang Chuanxi, Pan Haotian, Xu Tianhua, Zhang Jing, Guo Xiasheng, Tu Juan, Zhang Dong, Kong Xiangqing, Zhou Bin, Sun Wei

Abstract excerpt

Vascular events can trigger a pathological phenotypic switch in vascular smooth muscle cells (VSMCs), decreasing and disrupting the plasticity and diversity of vascular networks. The development of novel therapeutic approaches is necessary to prevent these changes. We aimed to investigate the effects and associated mechanisms of low-intensity pulsed ultrasound (LIPUS) irradiation on the angiotensin II...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Muscle, Smooth, Vascular

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Share to Rats, Sprague-Dawley

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Source

Identifiers

PMID: 34547245
DOI: 10.1016/j.ejphar.2021.174509

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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