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Non-invasive diagnostic tool for Parkinson’s disease by sebum RNA profile with machine learning

20 Sept 2021

Abstract excerpt

Parkinson's disease (PD) is a progressive neurodegenerative disease presenting with motor and non-motor symptoms, including skin disorders (seborrheic dermatitis, bullous pemphigoid, and rosacea), skin pathological changes (decreased nerve endings and alpha-synuclein deposition), and metabolic changes of sebum. Recently, a transcriptome method using RNA in skin surface lipids (SSL-RNAs) which can be obtained...

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PMID: 34545158
DOI: 10.1038/s41598-021-98423-9

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