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Article

Sebum: a window into dysregulation of lipid metabolism in Parkinson’s disease

2020-06-29

Abstract excerpt

A metabolomics profiling approach was conducted to identify diagnostic biomarkers of PD from sebum, a non-invasively available biofluid. In this study, we used liquid chromatography-mass spectrometry (LC-MS) to analyse 274 samples from participants (80 drug naïve PD, 138 medicated PD and 56 well matched control subjects) and detected metabolites that could predict PD phenotype. Partial least squares-discrimi...

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Literature Corpus work
f76d76b4-f581-5622-a86d-37367da4944f
DOI
10.26434/chemrxiv.11603613.v2
Open publication

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Sebum: a window into dysregulation of lipid metabolism in Parkinson’s diseaseDOI 10.26434/chemrxiv.11603613.v2
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