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Article

CNS Hypomyelination Disrupts Axonal Conduction and Behavior in Larval Zebrafish.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 3 Nov 2021

Madden M E, Suminaite D, Ortiz E, Early J J, Koudelka S, Livesey M R, Bianco I H, Granato M, Lyons D A

Abstract excerpt

Myelination is essential for central nervous system (CNS) formation, health and function. As a model organism, larval zebrafish have been extensively employed to investigate the molecular and cellular basis of CNS myelination, because of their genetic tractability and suitability for non-invasive live cell imaging. However, it has not been assessed to what extent CNS myelination affects neural circuit function in...

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Identifiers

PMID: 34544838
DOI: 10.1523/JNEUROSCI.0842-21.2021
PMCID: PMC8570833

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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